Who all is playing this year and what are your opinions?

I'll be playing in an 8 man league, 16 rounds.

Starting Lineup will look like this:
QB
RB
RB/WR
WR
WR
TE
D/ST
K

8 Bench players.

It's not a PPR and the QB scoring is 4 points for a passing TD and 1 point for every 20 yards thrown.

Who are the must take first rounders?

I think picks 1-6 should be a running back. Bell, Lacy, Lynch, Peterson, Murray and Charles. (IMO)

If I get the 7th or 8th pick and Antonio Brown slides back I think I'll go with him and then try to get a decent RB on the way back through (snake draft).

I had a terrible QB situation last year so I'll probably try to get a top tier QB a early as the 3rd round if I can.