Absolutely. That would be the smartest thing he could do. Just swap the spots, Clinton as Vice, which will gear her up for 2016, which is what she ultimately wants, and appoint Biden Secratary of State, a job that I think he wants.
Another democrat milestone for them to get behind, a woman in the white house. If it happens it will be interesting to watch the coverage of Hillary as a vice candidate in comparison to the coverage that Palin received.