Will teams play in empty stadiums by design? Will there be a season? Will the draft be closed to the public? Will this effect contracts? Suggestions?
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Will teams play in empty stadiums by design? Will there be a season? Will the draft be closed to the public? Will this effect contracts? Suggestions?
Me too man. Not to get to political but I find it very concerning that most of our medicines/antibiotics are produced and shipped in from China. We've allowed this to happen to ourselves, now with no shipping we have no way of getting our meds and no way to produce them here quickly as our manufacturing got moved to other countries. This could turn pretty bad very quickly if they don't get it under control soon.
Nothing will be different.
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This is one of the most irresponsible media driven panics in some time. Wash your hands.
Reminds me of when satanic cults were supposed to be carving a bloody swathe through small towns.
Wash hands, touch you face as little as possible, and for shit sake, stay away from social media.
I'm not sure I'd go that far.
No fans at Series A matches, Italy sporting events until April 3 due to coronavirus.
All sporting events in Italy -- including Serie A football matches -- will take place without fans present for at least the next month due to the coronavirus outbreak in the country, the Italian government announced Wednesday.
https://www.espn.com/soccer/italian-...to-coronavirus
It absolutely is a media driven panic. People are hoarding masks that are totally ineffective in stopping anything virus related. There are shortages of bottled water. During the height of the outbreak in Wuhan, the water supply was never infected or disrupted. Hand sanitizer, which is often extremely ineffective against viruses is being bought out of stores. There are media predictions of millions of deaths. This is just all irresponsible and ridiculous.
The data collected so far indicates that the mortality rate is far far far lower than originally estimated. If you look at the Diamond Princess cruise ship as a controlled case study (morbid, but true), you can see that the mortality rate on this virus is far lower - under 1% than is and has been reported in most major media outlets.
Should we all attempt to avoid large group gatherings until we understand the full nature of this particular virus? Sure, can't hurt. Will there be major disruptions to the economy and individual lives? Almost certainly. But this is not the first 15 minutes of some apocalyptic zombie movie like many seem to think it is or will become. This is not the end times. It is simply a previously unseen version of type of virus that we are very familiar with and while no one is entirely sure of how this will play out, it is not uncharted territory here. SARS was the exact same type of virus and spread in a similar manner; yet people did not freak out to this degree. I think that "viral" media bits are being spread about this viruses and people are losing their minds.
That's all I'm talking about. And those things could seriously effect the coming season.
BTW, if the weather forecaster on any channel here in New England predicts more than 8 inches of snow the local Super Markets run out of milk and bread in a matter of hours. Is that media driven, or is it the way people are?
Well, people are idiots. Especially in large numbers. So there is that. But the media doesn't help. My local news is breathless reporting updates every few hours. We don't report constantly on the flu. I mean people are all over the internet gargling with bleach and hoarding food in bunkers over this. So sure, people are dumb and panicky creatures but the "Outbreak 2020: Will Your Entire Family Die?" storylines coming out of "news" organizations and then shared at light speed is certainly not helping.
I figure I have downplayed this repeatedly to friends and family members. This almost certainly guarantees that I get it. I guess I will let you all know how it turns out.
Here is some context that is missing from almost all typical coronavirus reports: (https://www.hopkinsmedicine.org/heal...019-vs-the-flu)
COVID-19: Approximately 107,644 cases worldwide; 437 cases in the U.S. as of Mar. 8, 2020.
Flu: Estimated 1 billion cases worldwide; 9.3 million to 45 million cases in the U.S. per year.
Was it CNN or MSNBC that drove Xi Jinping to panic by quarantining 50 million people? :rolleyes:
Or did Fox News cause Italy to flip out and place a quarter of the population on lockdown this weekend?
Governments taking those kind of economic hits would seem to indicate they are taking this to be more serious than the annual flu season, presumably because there is no vaccine and some of the usual barriers to containment are not available
I don’t know. Certainly world perception was a major component of the decision making process.
Quarantine doesn’t always mean panic.
But people are taking about power and water turning off. Food supplies running out. I’ve seen people claim 1 in 5 of us are as good as dead.
Lots of people are going to get sick. Older people with compromised immune systems will die. Children and healthy adults are going to miss about 14 days of school or work.
But people are talking about this like we all should rewatch “The Walking Dead” like it’s an instructional manual.
People flip out about lots of stuff, like buying a month’s supply of bread when an inch of snow is predicted in Atlanta, without the media egging them on
My point is I do not recall the CDC telling anyone over 60 to stay home as much as possible at the start of every flu season
https://www.cnn.com/2020/03/06/healt...ing/index.html
Blaming the media for this supports certain narratives of those who for less than altruistic reasons may want to minimize any impact, but it would appear this is regarded by responsible people, as opposed to just those who draw worst case scenario inferences out of any event, to potentially be something that merits consideration of extraordinary actions
No doubt about it.
Compared to the potential loss of life, and disruption, what I'm going to say is relatively unimportant but: Take Brady's free agency for example. How would you write up a contract in the next few weeks, or even perhaps months? And what would you risk paying him? Seems like a game changer to me.
But none of these proposed actions are extraordinary. These are totally standard normal responses by leading health agencies to viral outbreaks. Limit contact between people. Prepare for a mass wave to roll through the population, etc. etc. This is the same situation we saw with SARS, H1N1, and several others over the past 10-15 years. And each time the fear and paranoia gets worse and the spread of useful information goes way down.
Certainly this is serious and sober business that should be handled by qualified and trained people. We know that it is not because the current administration gutted the agencies that would normally be doing this work. So sure, I get that the powers that be are really really hoping this is just kinda blows over. But the difference in the tone, tenor, and context of information coming out of the medical community and then just picking a random article off the internet is vast. One is just short of saying we all need to run for the hills and life as we know it is about to collapse and the other is along the lines of a lot of people are going to get the flu, hospitals will be pushed well over capacity, and then people will start to get better.
Doing what? Reacting in a totally normal and logic based series of decisions for a viral contagion?
Again, there will be impacts on daily life, but this is not a cause for pants ruining fear and chaos. All I am saying is that I refuse to freak out about this until someone who actually knows the difference between a virus and a bacteria tells me it is time to freak out.
I'm not debating the logic of any actions by governmental health agencies across the globe. I'm saying there have been unprecedented actions, at least in my memory. For example, closing down, restricting movement in and out, of several provinces in Italy involving millions of people. Playing soccer games in empty stadiums. Closed schools in Japan. So on and so forth.
Edit to add: I'm not telling anyone to freak out. I'm saying, pay attention, that's all.
Well, here's an example of how stupid the reactions to this virus are going.
https://finance.yahoo.com/news/ammun...133400231.html
Now, I'm a pretty good shot, but I don't think I'm good enough to draw and shoot on target to get that virus before I inhale it!
https://www.marketwatch.com/story/th...and-2020-03-06
A mix of legacy drugmakers and small startups have stepped forward with plans to develop vaccines or treatments that target the infection caused by the novel coronavirus.
COVID-19, which was first detected in December in Wuhan, China, has sickened more than 100,000 people worldwide and killed at least 3,400. There are no Food and Drug Administration-approved vaccines or therapies for the disease.
Read more of MarketWatch’s coverage of COVID-19.
In the U.S., the companies that are initiating development have received funding from two organizations: the Biomedical Advanced Research and Development Authority (BARDA), which is a division of the Department of Health and Human Services, and the National Institute of Allergy and Infectious Diseases (NIAID), a division of the National Institutes of Health. Some companies have received funding from Coalition for Epidemic Preparedness Innovations (CEPI), a global organization based in Oslo. Other companies are funding trials by themselves or through partnerships with other life sciences companies.
Here are some of the companies developing treatments or vaccines in the U.S. for COVID-19:
Company: Gilead Sciences Inc. GILD, -5.585%
Type: Treatment
Stage: Phase 3 clinical trials
Name: remdesivir
Background: Gilead is a longtime drug maker that is best known for developing the first major cure for hepatitis-C in Sovaldi, a therapy that changed the standard of care for that disease but also kicked off the national debate about drug pricing. The company has experience developing and marketing HIV drugs, including Truvada for pre-exposure prophylaxis (PrEP), its preventive HIV medicine. Along with U.S. trials, Gilead is conducting a randomized, controlled clinical trial in Wuhan, testing remdesivir as a treatment for mild to moderate forms of pneumonia in people with the virus. The trial was given the go-ahead by China’s Food and Drug Administration in February.
Clinical trials:
1. On Feb. 21, the National Institute of Allergy and Infectious Diseases started enrolling patients in a randomized, double-blind, placebo-controlled Phase 3 trial evaluating 394 hospitalized patients with COVID-19 at up to 50 sites worldwide. The trial is expected to conclude April 1, 2023. Sites include the National Institutes of Health in Bethesda, Md., (not recruiting), the University of Nebraska Medical Center in Omaha (recruiting), the University of Texas Medical Branch in Galveston (not recruiting), and Providence Sacred Heart Medical Center in Spokane (recruiting).
2. On March 3, Gilead said a randomized, open-label Phase 3 trial will evaluate remdesivir in 600 patients with moderate COVID-19. The trial is expected to start enrolling patients in March, with results to come in May.
3. On March 3, Gilead said a randomized, open-label Phase 3 trial will evaluate remdesivir in 400 patients with severe COVID-19. The trial is expected to start enrolling patients in March, with results in May.
Year-to-date stock performance: Shares of Gilead are up 17.6%.
Company: GlaxoSmithKline GSK, -1.970%
Type: Pandemic adjuvant platform for vaccines
Name: AS03 Adjuvant System
Background: GSK is another leading vaccine maker, having brought to market vaccines for human papillomavirus (HPV) and the seasonal flu, among others. On Feb. 3, it said the CEPI-funded University of Queensland will have access to the British drugmaker’s vaccine adjuvant platform technology, which is believed to both strengthen the response of a vaccine and limit the amount of vaccine needed per dose. On Feb. 24, GSK said that Clover Biopharmaceuticals Inc., a Chinese biotechnology company, is also using adjuvant technology in combination with its vaccine candidate, COVID-19 S-Trimer, in preclinical studies. Dr. Thomas Breuer, chief medical officer for GSK Vaccines, is leading work on vaccines and the adjuvant platform.
Year-to-date stock performance: Shares of GSK have tumbled 12.8%.
Company: Inovio Pharmaceuticals Inc. INO, -21.576%
Type: DNA-based vaccine
Stage: Preclinical
Name: INO-4800
Background: Another CEPI grantee, Inovio has said it already began preclinical testing and small-scale manufacturing.
Timeline: Inovio develops immunotherapies and vaccines but hasn’t yet had a product approved for treatment. For INO-4800, preclinical testing was performed between Jan. 23 and Feb. 29. The company plans to begin clinical trials in the U.S. with 30 participants in April. It also plans to launch human trials in China and South Korea that same month, and that it has a total of 3,000 doses prepared for the trials in the three countries. Inovio said it expects to have the first results from the trial in the fall and to have 1 million does of the vaccine ready for additional clinical trials or emergency use by the end of the year.
Year-to-date stock performance: Shares of Inovio have soared 278.2%.
Company: Johnson & Johnson JNJ, -2.570%
Type: Vaccine
Name: TBD (“We are still in the process of identifying a vaccine candidate, so no there is no name at this time,” a spokesman said March 4.)
Background: On Feb. 11, J&J said it is working with BARDA to test its vaccine candidate, with both organizations providing funding for research and development and the public-health organization funding the Phase 1 trials. Similar to GSK, J&J’s AdVac and PER. C6 technologies are used to improve the development process for a vaccine and were also used to develop J&J’s experimental Ebola vaccine. “We are also in discussions with other partners, that if we have a vaccine candidate with potential, we aim to make it accessible to China and other parts of the world,” Dr. Paul Stoffels, J&J’s chief scientific officer, said in a statement. J&J also said Feb. 18 that it is partnering with BARDA on a project that aims to screen existing antiviral medications, including experimental or approved therapies, that may be effective against COVID-19.
Timeline: The company aims to start a Phase 1 clinical trial by the end of 2020, “compared to the typical five to seven years it takes for this milestone in vaccine development,” Stoffels said on Dr. Paul Stoffels, J&J’s chief scientific officer and leader of J&J’s global COVID-19 response, said March 2.
Year-to-date stock performance: Shares of J&J are down 4.8%.
Company: Moderna Inc. MRNA, -10.081%
Type: RNA-based vaccine candidate
Stage: Preclinical
Name: mRNA-1273
Background: On Jan. 23, Moderna received funding from CEPI to develop an mRNA vaccine against COVID-19. On Feb. 24, it said it had shipped the first batch of mRNA-1273 to the NIAID for a Phase 1 clinical trial in the U.S.
Clinical trials: On Feb. 21, the NIAID said it would begin enrolling 45 healthy adult patients in an open-label Phase I clinical trial at one location to test mRNA-1273 as a vaccine for COVID-19 on March 19. The trial is expected to conclude June 1, 2021. Participants will be followed for one year. The trial will be conducted at Kaiser Permanente Washington Health Research Institute in Seattle.
Year-to-date stock performance: Moderna’s shares have gained 45.7%.
Company: Regeneron Pharmaceuticals Inc. REGN, -2.271%
Type: Treatment
Stage: Preclinical
Name: No name yet
Background: On Feb. 4, Regeneron announced it is working on developing monoclonal antibodies as treatments for COVID-19. The company’s VelocImmune platform uses genetically-engineered mice with humanized immune systems in preclinical testing. “We are aiming to have hundreds of thousands of prophylactic doses ready for human testing by end of August,” a spokesperson said. Christos Kyratsous, VP of infectious disease R&D and viral vector technology, is running the project.
Year-to-date stock performance: Regeneron’s shares are up 27.8%.
Company: Sanofi SNY, -4.284%
Type: Vaccine
Stage: Preclinical
Name: No name yet
Background: Starting Feb. 18, Sanofi is working with BARDA to test a preclinical vaccine candidate for severe acute respiratory syndrome (SARS) for COVID-19 using its recombinant DNA platform. It has a long history of producing vaccines in its Sanofi Pasteur business and acquired this candidate through its 2017 acquisition of Protein Sciences for $750 million. The French drugmaker previously worked with the organization on flu vaccines. Scientists in Meriden, Ct., are working on the vaccine; David Loew, Sanofi Pasteur’s EVP, is leading the project.
Timeline: A spokesperson said Sanofi aims to put a vaccine into a Phase 1 clinical trial between March 2021 and August 2021.
Year-to-date stock performance: Shares of Sanofi are down 4.3%.
Company: Takeda Pharmaceutical Company Ltd. TAK, -1.572%
Type: Treatment
Stage: Preclinical
Name: TAK-888
Background: Takeda is one of the most recent entrants to the race to develop a treatment for COVID-19. The Japanese drugmaker said March 4 it plans to test hyperimmune globulins for people who are at high risk for infection. As part of its research, which will be performed in Georgia, Takeda said it would need access to plasma from people who have recovered from COVID-19 or those who have received a vaccine if one is developed. Dr. Rajeev Venkayya, president of Takeda’s vaccine business, is the co-lead of the company’s COVID-19 response team. Like J&J, Takeda plans to examine whether other therapies, both experimental or with regulatory approval, may have treatment potential.
Year-to-date stock performance: Shares of Takeda are down 8.7%.
Company: Vir Biotechnology Inc. VIR, -12.47%
Type: Treatment
Stage: Preclinical
Background: Vir said Feb. 25 it is collaborating with Shanghai-based WuXi Biologics to test monoclonal antibodies as a treatment for COVID-19. If the treatment is approved, WuXi will commercialize it in China, while Vir will have marketing rights for the rest of the world. The preclinical company is run by George Scangos, the former CEO of Biogen.
Year-to-date stock performance: Vir shares have jumped 279%.
https://www.ibtimes.sg/who-says-ther...d-people-40581
The World Health Organisation has said there is no evidence of "reinfected" cases of coronavirus in China, after reports said earlier this week a young man in Wuhan died of coronavirus five days after he was discharged from a hospital.
"From the evidence we have, those cases were not reinfected," Maria Van Kerkhove, acting head of WHO's emerging diseases unit, said. She also suggested that initial tests that showed negative results could have been wrong in the first place
Well, I'm not an epidemiologist (nor do I play one on TV), but I do understand how the math works. With an R-0 of 2, it will be everywhere by summer. So once the preseason starts, everyone will have already been exposed.
Here's a decent video explaining the math:
https://www.youtube.com/watch?v=Kas0tIxDvrg
It should not affect a thing. This is the stupidest, most self-inflicted mass hysteria that I have seen in my entire life.
I mean, for Christ's sake, if you are afraid of dying from Coronavirus, that is literally 20 times less likely than being struck by lightning. Go buy a goddamn lottery ticket if you're into one-in-a-million chances.
This is almost entirely the result of shamelessly irresponsible reporting and fearmongering. Anything to get a click - truly a new low. Buy airline stocks, they're all down 50% for no reason.
They have locked down Italy completely. Also in Italy inmates have rioted, killed some guards, and taken some as hostages. I think everyone needs to calm down and take a deep breath.
You can still travel into and out of Italy. It is just only on necessary and unavoidable reasons https://www.bbc.com/news/world-europe-51810673
"The government has said only those with a valid work or family reason that cannot be postponed will be permitted to travel. Passengers departing on flights, except temporary visitors, will have to justify themselves, as will all those arriving by plane. There are controls at train stations to check temperatures. Cruise ships are forbidden to dock at various ports."
It appears that it may have only been inmates that died as a result of drug overdoses during the riots/protests over the cessation of visiting privileges to the prison. No mention of guard deaths or hostage situations:
"Earlier on Monday, six inmates died amid riots at prisons across the country after authorities suspended all visits as part of attempts to control the spread of the disease. The trouble began in the northern city of Modena after inmates at the Sant'Anna prison were told that all visits had been suspended. Three people were reported to have died at the prison, while a further three died after being transferred from there. It is thought that at least two of the dead lost their lives to drug overdoses after they raided a prison hospital for the heroin substitute methadone."
See how this gets all overblown, even out of a desire to know the most information possible? The headlines make us think that no one can go into or out of Italy - except you can. Massive riot at prison! Oh. Wait, maybe it was just a little riot and some drug overdoses during the confusion.
This stuff is not good, but the manipulation of headline and lede paragraph tone and content can change how it impacts.
https://www.reuters.com/article/us-h...-idUSKBN20W1JP
Inmates, many angered by restrictions on family visits, went on the rampage and started fires from Sunday into Monday, authorities said. In one prison, inmates took guards hostage and in another some escaped.
By Monday afternoon, violence that started at the heart of the coronavirus outbreak in northern Italy had spread south, hitting more than 25 penitentiaries nationwide.
Justice Minister Alfonso Bonafede said the government was open to discussing prison conditions but the rebellions had to stop.
In a sign of the political pressures piling onto his coalition government, the leader of the far-right opposition League, Matteo Salvini, called for an “iron fist” response.
Yeah. I did see what you found. It is just confounding and odd that you can't find the same information from source to source. Clear there were riots and hostages were (briefly?) taken.
No matter how hard you look, it just seems like every article is constructed with the conclusion in mind and the content is shaped to fit that.
I think its time the Pres to address the nation to try and quill this ramping up of fear. Not even sure how it will help though to be honest, our nation is pretty split at the moment, so half will believe him the other half will call him a liar and freak out. Delicate situation that the media could go a long ways in helping, but so far they are only showing horror stories of being trapped on boats and what not.
Sounds like good news to me.
https://nypost.com/2020/03/08/coronavirus-going-to-hit-its-peak-and-start-falling-sooner-than-you-think/
Nations are closing borders, stocks are plummeting and a New York Times headline reads: “The Coronavirus Has Put the World’s Economy in Survival Mode.” Both political parties have realized the crisis could severely impact the November elections — House, Senate, presidency. And sacré bleu, they’ve even shuttered the Louvre!
Some of these reactions are understand*able, much of it pure hysteria. Meanwhile, the spread of the virus continues to slow.
More than 18,000 Americans have died from this season’s generic flu so far, according to the latest data from the Centers for Disease Control and Prevention. In 2018, the CDC estimated, there were 80,000 flu deaths. That’s against 19 coronavirus deaths so far, from about 470 cases.
Worldwide, there have been about 3,400 coronavirus deaths, out of about 100,000 identified cases. Flu, by comparison, grimly reaps about 291,000 to 646,000 annually.
China is the origin of the virus and still accounts for over 80 percent of cases and deaths. But its cases peaked and began *declining more than a month ago, according to data presented by the Canadian epidemiologist who spearheaded the World Health Organization’s coronavirus mission to China. Fewer than 200 new cases are reported daily, down from a peak of 4,000.
Subsequent countries will follow this same pattern, in what’s called Farr’s Law. First formulated in 1840 and ignored in *every epidemic hysteria since, the law states that epidemics tend to rise and fall in a roughly symmetrical pattern or bell-shaped curve. AIDS, SARS, Ebola — they all followed that pattern. So does seasonal flu each year.
Clearly, flu is vastly more contagious than the new coronavirus, as the WHO has noted. Consider that the first known coronavirus cases date back to early December, and since then, the virus has *afflicted fewer people in total than flu does in a few days. Oh, and why are there no flu quarantines? Because it’s so contagious, it would be impossible.
As for death rates, as I first noted in these pages on Jan. 24, you can’t employ simple math — as everyone is doing — and look at deaths versus cases because those are *reported cases. With both flu and assuredly with coronavirus, the great majority of those infected have symptoms so mild — if any — that they don’t seek medical attention and don’t get counted in the caseload.
Furthermore, those calculating rates *ignore the importance of good health care. Given that the vast majority of cases have occurred in a country with poor health care, that’s going to dramatically exaggerate the death rate.
The rate also varies tremendously according to age, with a Chinese government analysis showing 0.2 percent deaths below age 40 but 14.8 percent above 80. A study published last month in the Journal of the American Medical Association found zero deaths worldwide among children 9 and under. Zero.
Like the flu, the coronavirus is afflicting high-risk groups: the elderly, those with *underlying health conditions like diabetes or heart disease and those with compromised immune systems. Are there exceptions? Sure. But that’s the case with almost every complex biological phenomenon of the kind.
More good news. This month, the Northern Hemisphere, which includes the countries with the most cases, starts heating up. Almost all respiratory viruses hate warm and moist weather. That’s why flu dies out in America every year by May at the latest and probably why Latin America has reported only 25 coronavirus cases. The Philippines, where I live, has about a third of the US population, but it’s so damned hot and humid here, so far we have had no confirmed cases of internal transmission.
The only questions are what the impact will be in the Southern Hemisphere, where far fewer people live, and whether it will *return to the north in the fall.
Still, if you want to try to reduce your *low risk even further, then use what works against flu and colds. Both the surgeon general and head of the CDC have advised we nix the masks; they don’t work. Instead, wash your hands with hot water and soap or an alcohol solution for at least 10 to 20 seconds. That way you won’t spread any germs when you use the TV remote to flip off the latest hysterical news report.
Man, I enjoyed reading that TWICE!
Yeah, this is nuts remember when Ebola was going to take us all out.
Normally, I would say "Absolutely". But during the press conference where he introduced the VP as the new point person, he spoke for less than a couple of minutes and then just left in the middle. Like he literally, waved goodbye, turned, and walked out of the room. Couldn't be clearer that this President has zero interest in this particular issue. To be clear, that is not to say that his government is doing nothing -- they are doing whatever they can. But I just don't think that Trump has any interest in thinking or talking about this stuff.